套件：fsa（1.15.9+dfsg-6）

[ 原始碼： fsa  ]

Fast Statistical Alignment of protein, RNA or DNA sequences

FSA is a probabilistic multiple sequence alignment algorithm which uses a "distance-based" approach to aligning homologous protein, RNA or DNA sequences. Much as distance-based phylogenetic reconstruction methods like Neighbor-Joining build a phylogeny using only pairwise divergence estimates, FSA builds a multiple alignment using only pairwise estimations of homology. This is made possible by the sequence annealing technique for constructing a multiple alignment from pairwise comparisons, developed by Ariel Schwartz.

FSA brings the high accuracies previously available only for small-scale analyses of proteins or RNAs to large-scale problems such as aligning thousands of sequences or megabase-long sequences. FSA introduces several novel methods for constructing better alignments:

 * FSA uses machine-learning techniques to estimate gap and
   substitution parameters on the fly for each set of input sequences.
   This "query-specific learning" alignment method makes FSA very robust:
   it can produce superior alignments of sets of homologous sequences
   which are subject to very different evolutionary constraints.
 * FSA is capable of aligning hundreds or even thousands of sequences
   using a randomized inference algorithm to reduce the computational
   cost of multiple alignment. This randomized inference can be over ten
   times faster than a direct approach with little loss of accuracy.
 * FSA can quickly align very long sequences using the "anchor
   annealing" technique for resolving anchors and projecting them with
   transitive anchoring. It then stitches together the alignment between
   the anchors using the methods described above.
 * The included GUI, MAD (Multiple Alignment Display), can display the
   intermediate alignments produced by FSA, where each character is
   colored according to the probability that it is correctly aligned

其他與 fsa 有關的套件

• dep: exonerate

  generic tool for pairwise sequence comparison

• dep: libc6 (>= 2.29) [除 i386]

  GNU C 函式庫：共用函式庫
  同時作為一個虛擬套件由這些套件填實： libc6-udeb

  dep: libc6 (>= 2.4) [i386]

• dep: libgcc-s1 (>= 3.0) [除 armel, armhf]

  GCC 支援函式庫

  dep: libgcc-s1 (>= 3.5) [armel, armhf]

• dep: libstdc++6 (>= 5.2)

  GNU Standard C++ Library v3

• dep: mummer

  Efficient sequence alignment of full genomes

• rec: med-config (>= 2.1)

  Debian Med general config package

下載 fsa

下載可用於所有硬體架構的

硬體架構	套件大小	安裝後大小	檔案
amd64	683。5 kB	4，254。0 kB	[檔案列表]
arm64	580。4 kB	3，807。0 kB	[檔案列表]
armel	570。9 kB	3，752。0 kB	[檔案列表]
armhf	572。1 kB	2，895。0 kB	[檔案列表]
i386	681。5 kB	4，408。0 kB	[檔案列表]
mips64el	607。1 kB	4，993。0 kB	[檔案列表]
mipsel	604。8 kB	4，811。0 kB	[檔案列表]
ppc64el	631。8 kB	4，890。0 kB	[檔案列表]
s390x	582。8 kB	4，243。0 kB	[檔案列表]