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[ Source: minimap2  ]

Пакунок: minimap2 (2.17+dfsg-1)

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versatile pairwise aligner for genomic and spliced nucleotide sequences

Minimap2 is a versatile sequence alignment program that aligns DNA or mRNA sequences against a large reference database. Typical use cases include: (1) mapping PacBio or Oxford Nanopore genomic reads to the human genome; (2) finding overlaps between long reads with error rate up to ~15%; (3) splice-aware alignment of PacBio Iso-Seq or Nanopore cDNA or Direct RNA reads against a reference genome; (4) aligning Illumina single- or paired-end reads; (5) assembly-to-assembly alignment; (6) full- genome alignment between two closely related species with divergence below ~15%.

For ~10kb noisy reads sequences, minimap2 is tens of times faster than mainstream long-read mappers such as BLASR, BWA-MEM, NGMLR and GMAP. It is more accurate on simulated long reads and produces biologically meaningful alignment ready for downstream analyses. For >100bp Illumina short reads, minimap2 is three times as fast as BWA-MEM and Bowtie2, and as accurate on simulated data. Detailed evaluations are available from the minimap2 paper or the preprint.

Інші пакунки пов'язані з minimap2

  • depends
  • recommends
  • suggests
  • enhances

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amd64 366.4 kB500.0 kB [список файлів]
arm64 349.1 kB456.0 kB [список файлів]
armhf 348.1 kB411.0 kB [список файлів]
i386 374.1 kB527.0 kB [список файлів]
x32 (unofficial port) 364.8 kB495.0 kB [список файлів]