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Package: probcons (1.12-4)

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PROBabilistic CONSistency-based multiple sequence alignment

Tool for generating multiple alignments of protein sequences. Using a combination of probabilistic modeling and consistency-based alignment techniques, PROBCONS has achieved the highest accuracies of all alignment methods to date. On the BAliBASE benchmark alignment database, alignments produced by PROBCONS show statistically significant improvement over current programs, containing an average of 7% more correctly aligned columns than those of T-Coffee, 11% more correctly aligned columns than those of CLUSTAL W, and 14% more correctly aligned columns than those of DIALIGN. Probcons is published in Do, C.B., Mahabhashyam, M.S.P., Brudno, M., and Batzoglou, S. 2005. Genome Research 15: 330-340.

Tags: Field: Biology, Bioinformatics, Implemented in: C++, User Interface: Command Line, Role: Program, Scope: Utility, Purpose: Comparing, Supports Format: Plain Text

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Architecture Package Size Installed Size Files
amd64 180.8 kB428.0 kB [list of files]