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[ Source: rna-star  ]

Package: rna-star (2.5.2b+dfsg-1)

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ultrafast universal RNA-seq aligner

Spliced Transcripts Alignment to a Reference (STAR) software based on a previously undescribed RNA-seq alignment algorithm that uses sequential maximum mappable seed search in uncompressed suffix arrays followed by seed clustering and stitching procedure. STAR outperforms other aligners by a factor of >50 in mapping speed, aligning to the human genome 550 million 2 × 76 bp paired-end reads per hour on a modest 12-core server, while at the same time improving alignment sensitivity and precision. In addition to unbiased de novo detection of canonical junctions, STAR can discover non-canonical splices and chimeric (fusion) transcripts, and is also capable of mapping full-length RNA sequences. Using Roche 454 sequencing of reverse transcription polymerase chain reaction amplicons, the authors experimentally validated 1960 novel intergenic splice junctions with an 80-90% success rate, corroborating the high precision of the STAR mapping strategy.

Tags: Biology: Nucleic Acids, Field: Biology, field::biology:bioinformatics, implemented-in::c++, Role: Program, Purpose: use::analysing, works-with::biological-sequence

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Download for all available architectures
Architecture Package Size Installed Size Files
amd64 357.2 kB810.0 kB [list of files]
arm64 334.9 kB734.0 kB [list of files]
mips64el 338.8 kB841.0 kB [list of files]
ppc64el 348.3 kB822.0 kB [list of files]