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Programs for the removal of noise from 454 sequenced PCR amplicons

AmpliconNoise is a package of applications to clean up high-throughput sequence data. It consists of three main parts:

Pyronoise - does flowgram-based clustering to spot misreads SeqNoise - removes PCR point mutations Perseus - removes PCR chimeras without the need for a set of reference sequences

Previously there was a standalone "Pyronoise" by the same authors and this package includes an updated version. There is also a "Denoiser" in Qiime which is related but distinct.

Removing Noise From Pyrosequenced Amplicons Christopher Quince, Anders Lanzen, Russell J Davenport and Peter J Turnbaugh BMC Bioinformatics 2011, 12:38doi:10.1186/1471-2105-12-38

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