Paket: muscle (1:5.1.0-1)

[ Quellcode: muscle  ]

Multiple alignment program of protein sequences

MUSCLE is a multiple alignment program for protein sequences. MUSCLE stands for multiple sequence comparison by log-expectation. In the authors tests, MUSCLE achieved the highest scores of all tested programs on several alignment accuracy benchmarks, and is also one of the fastest programs out there.

Muscle v5 is a major re-write of MUSCLE based on new algorithms.

Users should be aware that command line arguments compared to version 3.x of MUSCLE have changed!

Highest accuracy, scalable to thousands of sequences

Compared to previous versions, Muscle v5 is much more accurate, is often faster, and scales to much larger datasets. At the time of writing (late 2021), Muscle v5 has the highest scores on multiple alignment benchmarks including Balibase, Bralibase, Prefab and Balifam. It can align tens of thousands of sequences with high accuracy on a low-cost commodity computer (say, an 8-core Intel CPU with 32 Gb RAM). On large datasets, Muscle v5 is 20-30% more accurate than MAFFT and Clustal-Omega.

Alignment ensembles

Muscle v5 can generate ensembles of high-accuracy alternative alignments. All replicates have equal average accuracy on benchmark test, including the MSA made with default parameters. By comparing results of downstream analysis (trees, structure prediction...) on different replicates, you can assess the effects of alignment errors on your study.

Markierungen: Biologie: Clustal/ALN, Proteine, Feld: field::biology, field::biology:bioinformatics, Implementiert in: implemented-in::c++, interface::commandline, Rolle: Programm, Zweck: Hilfswerkzeug, Zweck: use::comparing, works-with-format::plaintext, Arbeitet mit: Benötige eine zusätzliche Markierung

Andere Pakete mit Bezug zu muscle

• dep: libc6 (>= 2.34)

  GNU-C-Bibliothek: Laufzeitbibliotheken
  auch ein virtuelles Paket, bereitgestellt durch libc6-udeb

• dep: libgcc-s1 (>= 3.0) [nicht armel, armhf]

  GCC Support-Bibliothek

  dep: libgcc-s1 (>= 3.5) [armel, armhf]

• dep: libgomp1 (>= 4.9)

  Unterstützungsbibliothek für GCC OpenMP (GOMP)

• dep: libstdc++6 (>= 11)

  GNU-Implementierung der Standard-C++-Bibliothek (Version 3)

• enh: seaview

  Multiplatform interface for sequence alignment and phylogeny

• enh: t-coffee

  Multiple Sequence Alignment

muscle herunterladen

Download für alle verfügbaren Architekturen

Architektur	Paketgröße	Größe (installiert)	Dateien
amd64	290,4 kB	843,0 kB	[Liste der Dateien]
arm64	256,3 kB	859,0 kB	[Liste der Dateien]
armel	238,0 kB	794,0 kB	[Liste der Dateien]
armhf	242,3 kB	538,0 kB	[Liste der Dateien]
i386	303,8 kB	922,0 kB	[Liste der Dateien]
mips64el	278,3 kB	1.104,0 kB	[Liste der Dateien]
mipsel	276,8 kB	1.087,0 kB	[Liste der Dateien]
ppc64el	309,8 kB	1.051,0 kB	[Liste der Dateien]
s390x	260,2 kB	879,0 kB	[Liste der Dateien]