Package: poa (2.0+20060928-2)

Partial Order Alignment for multiple sequence alignment

POA is Partial Order Alignment, a fast program for multiple sequence alignment (MSA) in bioinformatics. Its advantages are speed, scalability, sensitivity, and the superior ability to handle branching / indels in the alignment. Partial order alignment is an approach to MSA, which can be combined with existing methods such as progressive alignment. POA optimally aligns a pair of MSAs and which therefore can be applied directly to progressive alignment methods such as CLUSTAL. For large alignments, Progressive POA is 10-30 times faster than CLUSTALW. POA is published in Bioinformatics. 2004 Jul 10;20(10):1546-56.

Tags: Field: Biology, Implemented in: C, User Interface: Command Line, Role: Program, Scope: Utility, Supports Format: Plain Text