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[ Source: melting  ]

Package: melting (4.2h-3)

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computing the melting temperature of nucleic acid duplex

This program computes, for a nucleic acid duplex, the enthalpy, the entropy and the melting temperature of the helix-coil transitions. Three types of hybridisation are possible: DNA/DNA, DNA/RNA, and RNA/RNA. The program first computes the hybridisation enthalpy and entropy from the elementary parameters of each Crick's pair by the nearest-neighbor method. Then the melting temperature is computed. The set of thermodynamic parameters can be easily changed, for instance following an experimental breakthrough. Melting was published in Le Novère N. (2001), Bioinformatics, 17: 1226-1227.

Tags: Biology: Nucleic Acids, Field: Biology, Molecular Biology, Implemented in: C, User Interface: Command Line, Role: Program, Scope: Utility, Purpose: Analysing, Supports Format: Plain Text

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Architecture Package Size Installed Size Files
alpha 211.3 kB604.0 kB [list of files]
amd64 210.8 kB596.0 kB [list of files]
arm 206.4 kB592.0 kB [list of files]
armel 211.5 kB596.0 kB [list of files]
hppa 210.8 kB596.0 kB [list of files]
i386 209.3 kB596.0 kB [list of files]
ia64 212.4 kB632.0 kB [list of files]
mips 210.6 kB600.0 kB [list of files]
mipsel 207.1 kB600.0 kB [list of files]
powerpc 207.4 kB596.0 kB [list of files]
s390 206.9 kB596.0 kB [list of files]
sparc 206.8 kB596.0 kB [list of files]